Browsing by Author "Yalcintepe, Sinem"
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The CYP4502D6*4 and*6 alleles are the molecular genetic markers for drug response: implications in colchicine non-responder FMF patients
Yalcintepe, Sinem; Ozdemir, Ozturk; Silan, Coskun; Ozen, Filiz; Uludag, Ahmet; Candan, Ferhan; Silan, Fatma (SPRINGER FRANCE, 2016)The cytochrome P450 2D6 (CYP2D6) is a cytochrome P450 enzyme involved in the oxidative biotransformation of the xenobiotics, carcinogens and various clinically important drugs. Patients are evaluated in three sub-groups ... -
Multiple Inherited Thrombophilic Gene Polymorphisms in Spontaneous Abortions in Turkish Population
Yalcintepe, Sinem; Ozdemir, Ozturk; Hacivelioglu, Servet Ozden; Akurut, Cisem; Koc, Evrim; Uludag, Ahmet; Cosar, Emine; Silan, Fatma (CELLULAR & MOLECULAR BIOLOGY RESEARCH CENTER, 2015)The aim of this study was to investigate the possible role of multiple inherited thrombophilic gene variations in women with unexplained spontaneous abortions. For this purpose, the Factor V Leiden (FVL) (rs6025), Prothrombin ...